Laboratory of Growth Regulators has been created in 1996 as a joint facility of the Faculty of Science, Palacký University and the Institute of Experimental Botany, Academy of Sciences of the Czech Republic.
Research program of the laboratory is aimed primarily at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. A representative of the latter, roscovitine (CYC202, seliciclib), is already undergoing phase II clinical trials as a novel anticancer drug by Cyclacel Pharmaceuticals, Inc. (under licence; for more information see actual Press Release). (more…)